Eyesore of the Month by James Howard Kunstler

“The Peter B. Lewis Building for Case Western Reserve University’s Weatherhead School of Management. Architect: Frank Gehry. If your dog had a tumor like this the vets would just shake their heads and put him to sleep.”

No kidding.
Note that this link may not link to the October 2005 eyesore come November.. I’ll try and remember to update it once a permalink is available.